PUBLICATIONS

Sharing discoveries that illuminate the brain.

#equal contribution, *corresponding author

Dopamine-mediated formation of a memory module in the nucleus accumbens for goal-directed navigation Jung K*, Krüssel S, Yoo S, An M, Burke B, Schappaugh N, Choi Y, Gu Z, Blackshaw S, Costa RM, Kwon HB*.
Nat Neurosci. 27(11):2178–2192 (2024)
This study demonstrates how dopamine signaling in the nucleus accumbens forms a memory module that supports goal-directed navigation.

목적지향적 탐색을 위한 도파민 매개 기억 모듈의 형성

Son S#, Nagahama K#, Lee J#, Jung K#, Kwak C, Kim J, Noh YW, Kim E, Lee S, Kwon HB, Heo WD.
Nat Methods. 21(2):353–360 (2024)
The study provides real-time in vivo insights into synaptic structure changes using advanced imaging techniques.

‘시냅샷 기술’로 기억, 인지 과정 실시간 관찰

Illustration related to Synapshot study
Jung K, Chang M, Steinecke A, Burke B, Choi Y, Oisi Y, Fitzpatrick D, Taniguchi H, Kwon HB.
Nat Neurosci. 26(8):1379–1393 (2023)
This paper identifies a cortical motif using axo-axonic inhibition to regulate adaptive behavioral control.
Valtcheva S#, Issa HA#, Bair-Marshall CJ, Martin KA, Jung K, Zhang Y, Kwon HB, Froemke RC.
Nature. 621(7980):788–795 (2023)
This study maps the circuit mechanism triggering maternal oxytocin release in response to pup distress.
Jung K#, Choi Y#, Kwon HB.
Front Cell Neurosci. 16:992409 (2022)
This work investigates how cortical circuits regulate chandelier cell output for neural code structuring.
Oh WC, Rodríguez G, Asede D, Jung K, Hwang IW, Ogelman R, Bolton MM, Kwon HB.
Cell Rep. 35(5):109074 (2021)
The study reveals how early-life stress affects dopamine circuitry and synaptic balance in the prefrontal cortex.
Kim J#, Lee S#, Jung K#, Oh WC, Kim N, Son S, Jo Y, Kwon HB, Heo WD.
Nat Commun. 10(1):211 (2019)
Visualizes GTPase activity across cells using biosensors, enabling real-time tracking of molecular signaling.
Jung K#, Jeong J, Kralik JD.
Front Comput Neurosci. 13:40 (2019)
A computational model showing how selective attention governs decision-making in complex, contextual tasks.
Jang H#, Jung K#, Jeong J, Park SK, Kralik JD, Jeong J.
Soc Cogn Affect Neurosci. 12(9):1428–1436 (2017)
Investigates how the nucleus accumbens shell modulates preference bias during decision-making.
Lee D#, Hyun JH#, Jung K, Hannan P, Kwon HB.
Nat Biotechnol. 35(9):858–863 (2017)
Develops a light- and calcium-sensitive system to selectively label and control neuron populations.

광유전학 기반 세포 활성 신경세포 추적 및 제어 기술 (iTango)

Lee D#, Creed M#, Jung K#, Stefanelli T, Wendler DJ, Oh WC, Mignocchi NL, Lüscher C, Kwon HB.
Nat Methods. 14(5):495–503 (2017)
Introduces methods for precisely targeting and manipulating neuromodulatory brain circuits.

광유전학 기반 GPCR 활성 신경세포 추적 및 제어 기술 (iTango)

Jung K, Jang H, Kralik JD, Jeong J.
PLoS Comput Biol. 10(8):e1003759 (2014)
Analyzes foraging behaviors to show bursty patterns and long-tailed inter-decision intervals in animals.
Jung K, Kralik JD.
PLoS One. 8(12):e83814 (2013)
Describes how rhesus macaques exhibit a preference for high-value options first when given choice.